Unless you can convince Airbnb that your mistake was an extenuating circumstance, I would advise you to keep the reservation. Not only is the calendar blocked but there is potentially a $100 fine if the cancellation is within 7 days of check-in. In addition, there is an automatic review on your listing saying that you cancelled a reservation. Search placement is also affected by cancellations. Airbnb does not look kindly on hosts who cancel since it really messes up guest travel plans. You certainly can appeal to Airbnb if this is your first cancellation. Here's a handy guide for contacting Airbnb:
https://community.airbnb.com/t5/Tips-Tricks/Contact-Airbnb-A-How-To-Guide/m-p/16165/highlight/false#...
You should also read up on host cancellations:
https://www.airbnb.com/help/article/990/how-do-the-cancellation-penalties-work
Good Luck!